Uppsala University hereby declares the following position to be open for application:
PhD position in Functional Genomics
at the Department of Medical Biochemistry and Microbiology, Uppsala Biomedical Center, starting date as soon as possible or according to agreement.
The department of Medical Biochemistry and Microbiology at Uppsala University (http://www.imbim.uu.se) has a broad research profile, pursuing research within three major areas – Genomics; Biochemistry and Molecular Cell Biology; Immunology and Microbiology. This categorization has a historical and organizational background, with numerous active scientific exchanges and collaborations between the three sections. In addition, much of the research is interdisciplinary in character and involves collaboration with other departments at Uppsala University and other universities. Core facilities for proteomics and transgenic animals are present at IMBIM, which also hosts the administrative functions and offices of the director of Science for Life Laboratory in Uppsala (SciLifeLab-U).
Project description: We are working with domestic dog as a model organism for identifying new pathways, genes and mutations behind human immunological and immune-mediated diseases. Dogs, as other domestic animals, have a genomic structure suitable for gene mapping. In addition, dogs also present the same spectrum of diseases as humans and nowadays even share our living-environment. Therefore, taking advantage of those characteristics may provide us knowledge of genetic risk factors underlying human immunological diseases. In general our approach goes from identifying risk loci in a dog breed all the way to providing functional evidence of an identified mutation contributing to the disease development. Our goal is to provide information necessary for the future development of genetic testing, diagnostics and therapy for the dogs. Furthermore, the ultimate goal is to provide functional genomic data of the same mutations, genes and pathways involved in development of human homologous diseases.
We are looking for a highly motivated person who is interested in pursuing a PhD in the field of Comparative Genetics and Functional Genomics. More specifically the main project would involve functional characterization of candidate mutations for Canine Lymphocytic Thyroiditis as well as comparative studies on human patients with the equivalent disease (Hashimoto’s Thyroiditis). Further information on the activity of the research group can be accessed at
http://www.imbim.uu.se/Research/+Genomics/Rosengren_Pielberg_Gerli/
Qualifications: The applicant should have an academic degree, e.g. MSc in Molecular Biology, or similar. Experience from experimental research, expression and functional studies, immunology and analysis of next-generation sequence data are considered as additional qualifications. Documented skills in oral and written English are required.
The application should include a curriculum vitae, copies of exams, degrees and grades, references and a short description of the applicant and his/her experience. Letters(s) of recommendation may be included. If the applicant has published scientific papers, they can also be included.
Information about education at the postgraduate level, admission requirements and admission decisions can be found at http://www.medfarm.uu.se/utbildning/forskarniva/
Selection of applicants will be done by the future tutor for the selected student in consultation with the postgraduate study group of the department. The Postgraduate Programmes Committee at the Disciplinary Domain of Medicine and Pharmacy will formally approve of the student’s admission.
Applications will be evaluated according to following criteria: fulfillment of qualifications, earlier experiences of work and/or research in relevant topic as well as personal suitability.
Salary will be according to local guidelines at Uppsala University.
The rules governing this process can be found (in Swedish) in Högskoleförordningen 5 Chapter 1-7 §§ and in University rules http://regler.uu.se/.
For more information, please contact: Assistant Professor Gerli R. Pielberg, phn.+46184714575 or e-mail gerli.pielberg@imbim.uu.se . Union representatives are Anders Grundström, Saco, phone +46-(0)18-471 5380, Carin Söderhäll, TCO/ST, phone +46-(0)18-471 1996, and Stefan Djurström, Seko, phone +46-(0)18-471 3315.
You are welcome to submit your application no later than 28 February, 2012, UFV-PA 2012/173. Use the link below to access the application form.
PhD position in Functional Genomics